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. 2022 Jun 26;81(9):1301–1312. doi: 10.1136/annrheumdis-2022-222460

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.

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Genetic correlation among the autoimmune and allergic diseases. (A) Histograms of the heritability and genetic correlation matrices of autoimmune and allergic diseases in BBJ (left panel) and UKB (right panel). (B) Dendrograms of the hierarchical clustering based on the genetic correlations in BBJ (left panel) and UKB (right panel). (C) Scatter plots describing the associations between the genetic correlations in BBJ (x-axis) and UKB (y-axis). Dots represent the estimates of the genetic correlation and whiskers represent 95% confidence intervals. The dots are coloured according to disease categories. AD, atopic dermatitis; BA, bronchial asthma; BBJ, BioBank Japan; GD, Grave’s diseases; PO, pollinosis; RA, rheumatoid arthritis; T1D, type 1 diabetes; UKB, UK Biobank.