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. 2022 Jun 26;81(9):1301–1312. doi: 10.1136/annrheumdis-2022-222460

Table 2.

Significantly enriched cell type in autoimmune and allergic diseases

Category Cell type P value
BA (UKB) PO (UKB) BA (BBJ)
T cell T.4Mem.Sp 3.8×10-6 2.5×10-4 0.0015
T cell T.4Mem44h62l.Sp 1.3×10-5 1.9×10-4 5.3×10-4
Natural killer cell NKT.4-.Sp 3.1×10-5 4.6×10-5 0.0048
Natural killer cell NKT.4+.Lv 3.5×10-5 1.1×10-4 0.019
T cell LN.TR.14w.B6 4.4×10-5 3.6×10-5 7.4×10-4
T cell ABD.TR.14w.B6 5.4×10-5 6.5×10-5 2.2×10-4
T cell T.4Mem44h62l.LN 1.4×10-4 5.6×10-4 0.0078
T cell CD4Control 3.3×10-4 9.1×10-5 0.0013
T cell T.8Mem.Sp 0.010 0.0064 1.5×10-4
T cell T.8Eff.Tbet+.Sp.OT1.d6LisOVA 0.053 0.051 1.5×10-4

P values satisfying the threshold of 0.05/292 for Bonferroni multiple testing are shown in bold.

BA, bronchial asthma; BBJ, BioBank Japan; PO, pollinosis; UKB, UK Biobank.