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Box and whisker plot of haemodynamic metrics including mPAP, CI, PVR, mean right atrial pressure, mixed venous oxygen saturation and Ees:Ea at baseline in groups. CI, cardiac index; Ea, arterial load; Ees, right ventricular elastance; HVHM, high-volume-high-mass; HVLM, high-volume-low-mass; LVHM, low-volume-high-mass; LVLM, low-volume-low-mass; mPAP, mean pulmonary arterial pressure; PVR, pulmonary vascular resistance. *P≤0.05; **P≤0.01; ***P≤0.001; ****P≤0.0001.
