Table 1.

Sequences of phage clones isolated by in vitro–in vivo combinatorial biopanning of the Ph.D.−12 phage display peptide library in an orthotopic murine pancreatic ductal adenocarcinoma model in vivo and human PSCs in vitro

Phage clone	Phage-displayed peptide sequence
PSC29,53,56,64,71,82,94,109			R	D	Y	H	P	R	D	H	T	A	T	W
PSC45						H	P	D	A	A	S	K	R	W	N	T	P
PSC28			L	Q	T	T	C	T	P	H	C	V	S	W
PSC1			D	S	Y	R	N	N	V	R	S	S	D	W
PSC14,79						N	Y	R	D	Y	S	S	E	S	R	S	L
PSC2							A	D	L	P	A	K	S	W	T	Y	L	Y
PSC13					A	E	T	P	G	S	S	I	K	W	I	T
PSC3							A	H	F	T	S	S	E	F	S	R	I	A
PSC44						S	M	D	P	W	T	K	S	F	Q	S	P
PSC7				H	L	S	R	P	N	M	S	N	T	S	A
PSC5		T	V	V	A	W	R	P	Y	H	D	T	N
PSC30			W	D	H	A	R	P	Y	T	D	L	A	G
PSC40	S	S	E	Y	F	Q	R	P	Q	S	A	G
PSC52										N	I	L	T	G	G	L	I	V	S	A	W
PSC128										N	I	S	L	D	I	H	F	A	H	L	K
PSC19				W	H	K	N	E	A	N	L	S	T	R	L
PSC47		S	H	E	G	M	S	T	V	N	L	S	A
PSC10,24,92									N	S	H	A	I	W	L	S	A	P	F	G
PSC25		G	L	G	T	L	A	P	N	S	H	I	A
PSC17		S	E	L	Y	G	G	M	T	R	G	M	F
PSC4	A	S	Y	S	S	G	P	H	T	V	Q	Y
PSC110			S	S	S	G	V	M	H	G	P	P	V	L
PSC9							G	M	H	G	K	C	Y	G	R	E	L	C
PSC16						H	M	S	H	G	E	G	S	R	M	Y	F
PSC23,26,39, 68,73,80,97,125,146,150						Q	V	N	G	L	G	E	R	S	Q	Q	M
PSC144		K	V	K	H	Q	P	N	P	L	G	P	M
PSC31					S	Q	V	S	V	L	P	D	N	H	D	T
PSC49,91,113,140,145						G	N	N	P	L	H	V	H	H	D	K	R
PSC11	S	L	K	H	F	G	Y	I	E	M	K	F
PSC117					F	S	V	D	T	M	I	R	Y	V	P	H
PSC20			D	V	F	V	G	R	T	M	Q	T	F	I
PSC114						F	D	V	T	M	D	A	W	T	T	S	L

Conserved residues and consensus motifs are shown in bold. Selected phage clones are highlighted with light grey shade.

PSC, pancreatic stellate cells.