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IC50, CC50, and SI values for AB-00047476 and AB-00011778a
| Parameter | Value for: |
|||||
|---|---|---|---|---|---|---|
| AB-00047476 |
AB-00011778 |
|||||
| 293T-ACE2 | A549-ACE2 | Calu3 | 293T-ACE2 | A549-ACE2 | Calu3 | |
| IC50 | 1 | 2.5 | 5 | 1 | 0.25 | 1 |
| CC50 | >30 | >30 | >30 | >50 | >30 | >30 |
| SI | >30 | >12 | >6 | >50 | >120 | 30 |
CC50 was calculated using four-parameter variable slope sigmoidal dose-response models based on MTT assays.
