FIG 1.

GHs potentiate antibiotic activity against P. aeruginosa biofilms in vitro. Dose-response matrix analyses of P. aeruginosa biofilms cotreated with 2-fold serial dilutions of either PslG_h-PelA_h or PslG_h-Ega3_h and 4-fold serial dilutions of ceftazidime or ciprofloxacin in a MBEC high-throughput assay as indicated are shown. Biofilm biomass was quantified with crystal violet staining. Colored squares represent the ratio of treated to untreated biofilms of ≥2 independent experiments. Lighter yellow boxes represent high biofilm biomass and darker green boxes represent low biofilm biomass, compared with untreated control wells.