FIGURE 3.

Resistance of individual mutations from Omicron spike protein to five types of antibodies (class 1, class 2, class 3, class 4, and NTD mAbs). The degree of resistance is represented by different colors. Resistance from strong to weak is indicated by red, orange, and yellow, respectively, while those favorable to antibody binding were blue. If the resistance strength is not marked, it indicates that there is little change in resistance to the antibody after the individual mutation. Mutations with strong resistance to NTD mAbs are G142D, Del143‐145, N211I, S477N, and N501Y; mutations with robust impedance to class 2 antibody are E484A and Q943R; L981F showed well binding ability to class 1 and class 3 antibodies. (The figure was drawn on “Adobe illustrator” tool)