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. 2022 Aug 8;8(9):1758–1814. doi: 10.1021/acsinfecdis.2c00204

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© 2022 The Authors. Published by American Chemical Society

Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).

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Overview of different methods for COVID-19 diagnosis. SARS-CoV-2 can be directly detected in humans using molecular approaches, such as RT-qPCR, DNA sequencing, RT-LAMP, CRISPR/Cas systems, and sensors. Imaging tests, including chest computed tomography (CT), have been widely used as a complementary approach to diagnose COVID-19 patients. Additionally, human antibodies produced against SARS-CoV-2 antigens can be detected in blood samples via serological methods, including enzyme-linked immunosorbent assay (ELISA), chemiluminescence immunoassay (CLIA), immunofluorescence assay (IFA), and lateral flow assay (LFA). This figure was created with Biorender.com.