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CAR T-cell product characterization.
| Subject 1 | Subject 2 | |
|---|---|---|
| Age (yr)/sex | 1/M | 6/M |
| Weight (kg) | 16 | 15.4 |
| Infused cells (×106) | 641 | 625 |
| Fresh/frozen | Frozen | Fresh |
| Formulation | 44 mL Normosol-R | 45 mL Normosol-R |
| 5 mL autologous plasma | 5 mL autologous plasma | |
| 1 mL DMSO | ||
| Production start (×106) | 20 | 20 |
| Production end (×106) | 2,729 | 6,560 |
| Transduction efficiency | 32.9% | 47.6% |
| CD4:CD8 | 1.77 | 0.89 |
