Fig. 4.

Axial T2-weighted images in a 74-year-old man with a suspicious lesion in the transition zone (PI-RADS 3, mostly based on DWI [third slice of ADC map containing the lesion attached for reference with a white cross indicating the single-click voxel with the quantitatively acquired lowest ADC value]) that proved to be non-significant PCa (based on MRI-TRUS fusion). A T2-weighted images without any segmentation. B Results of slice-by-slice manual lesion segmentation by an expert uroradiologist. C Results of 18-mm auto-fixed VOI lesion segmentation without DLM adjustment. D Deep learning–based total prostate segmentation. E Results of 18-mm auto-fixed VOI lesion segmentation with DLM adjustment