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. 2022 Aug 3;9:921550. doi: 10.3389/fnut.2022.921550

TABLE 3.

Relationship between HEI-2015 and gout among adults aged 20 years or older.

Variable OR (95% CI) P-value

Model 1 Model 2 Model 3
Sex (reference, female) <0.001
Male 2.743 (2.739, 2.748) 2.643 (2.639, 2.648) 3.027 (3.022, 3.033)
Age group (reference, 20–39 year) <0.001
40–59 year 5.204 (5.188, 5.220) 4.522 (4.508, 4.537) 3.68 (3.668, 3.692)
60–79 year 12.372 (12.334, 12.411) 9.993 (9.961, 10.025) 6.234 (6.213, 6.254)
80+ year 17.066 (17.002, 17.129) 15.729 (15.669, 15.790) 8.465 (8.431, 8.499)
Race (reference, non-Hispanic white) <0.001
Mexican American 0.430 (0.428, 0.432) 0.398 (0.396, 0.400) 0.452 (0.450, 0.454)
Non-Hispanic black 1.245 (1.242, 1.248) 1.231 (1.228, 1.234) 1.022 (1.019, 1.024)
Other 0.756 (0.753, 0.758) 0.828 (0.826, 0.830) 0.809 (0.807, 0.812)
Education (reference, <high school) <0.001
High school/GED 1.046 (1.044, 1.049) 1.056 (1.054, 1.059) 1.098 (1.095, 1.101)
College/AA degree 1.122 (1.120, 1.125) 1.113 (1.110, 1.115) 1.121 (1.118, 1.124)
College or above 0.932 (0.929, 0.934) 1.061 (1.059, 1.064) 1.152 (1.148, 1.155)
Family income (reference,0∼130% FPL) <0.001
>130∼350% FPL 0.703 (0.702, 0.705) 0.676 (0.674, 0.677) 0.722 (0.721, 0.724)
>350% FPL 0.700 (0.699, 0.702) 0.681 (0.679, 0.682) 0.774 (0.772, 0.776)
HEI category (reference, Q1) <0.001
Q2 0.910 (0.908, 0.912) 0.903 (0.901, 0.905) 0.888 (0.886, 0.890)
Q3 0.974 (0.972, 0.976) 1.01 (1.007, 1.012) 0.991 (0.989, 0.993)
Q4 0.832 (0.830, 0.834) 0.886 (0.884, 0.888) 0.878 (0.876, 0.880)
BMI (reference, normal weight) <0.001
Underweight 0.619 (0.611, 0.627) 0.689 (0.680, 0.698)
Overweight 1.678 (1.674, 1.683) 1.361 (1.358, 1.365)
Obese 3.062 (3.054, 3.069) 1.907 (1.902, 1.912)
Drink level (reference, none) <0.001
Light 0.822 (0.820, 0.823) 0.871 (0.869, 0.872)
Moderate 0.878 (0.876, 0.879) 0.913 (0.912, 0.915)
Heavy 1.314 (1.308, 1.320) 1.203 (1.197, 1.209)
Smoke status (reference, never) <0.001
Former 1.335 (1.332, 1.337) 1.266 (1.264, 1.268)
Current 1.019 (1.017, 1.022) 1.05 (1.047, 1.052)
CKD (reference, no) <0.001
Yes 2.051 (2.045, 2.057)
Diabetes (reference, no) <0.001
Yes 1.33 (1.327, 1.332)
Hypertension (reference, no) <0.001
Yes 2.304 (2.300, 2.308)
HUA (reference, no) <0.001
Yes 2.484 (2.480, 2.488)

FPL, family income to poverty; CI, confidence interval; OR, odds ratio; CKD, chronic kidney disease; Model 1, adjusted for demographic characteristics (sex, age group, race, education, family income); Model 2, adjusted for demographic characteristics (sex, age group, race, education, family income); BMI, smoking, and drinking status; Model 3, adjusted for demographic characteristics (sex, age group, race, education, family income); BMI, smoking, drinking status, hypertension, CKD, diabetes, and hyperuricemia.