Table 2.
Top 20 significantly upregulated genes in the human and murine SASP clusters. Multiple t-test with Benjamini–Hochberg adjustment
| Gene | avg_log2FC | Adj. p value |
|---|---|---|
| Human | ||
| S100A9 | 1.974317678 | 0 |
| CXCL8 | 1.817775253 | 0 |
| CST3 | 1.813835295 | 0 |
| TYROBP | 1.742773952 | 0 |
| LST1 | 1.704456515 | 0 |
| FCN1 | 1.704148119 | 0 |
| FCER1G | 1.698071186 | 0 |
| LYZ | 1.695879021 | 0 |
| CCL3 | 1.68109761 | 0 |
| S100A8 | 1.639167524 | 0 |
| CTSS | 1.605107533 | 0 |
| AIF1 | 1.537560282 | 0 |
| S100A12 | 1.501013381 | 0 |
| SAT1 | 1.475740324 | 0 |
| G0S2 | 1.471768259 | 0 |
| S100A11 | 1.426583167 | 0 |
| PSAP | 1.412156019 | 0 |
| NEAT1 | 1.402008889 | 0 |
| CSTA | 1.346171061 | 0 |
| SERPINA1 | 1.343012763 | 0 |
| Murine | ||
| Ccl2 | 1.385385456 | 4.4042E-274 |
| Cxcl14 | 1.348765531 | 0 |
| Cxcl12 | 1.348099221 | 0 |
| Hp | 1.32967138 | 2.6772E-298 |
| Trf | 1.32483506 | 6.8972E-280 |
| Serping1 | 1.304871038 | 0 |
| Mt1 | 1.294617837 | 0 |
| Tmem176b | 1.238330075 | 0 |
| Mt2 | 1.224158694 | 0 |
| Igfbp4 | 1.210905773 | 0 |
| Grem1 | 1.207056724 | 0 |
| Cd302 | 1.195220747 | 0 |
| Apoe | 1.163062993 | 0 |
| Msmp | 1.16240244 | 3.2104E-194 |
| Adipoq | 1.140888365 | 7.4114E-283 |
| Cyr61 | 1.136426625 | 0 |
| Gas6 | 1.110474329 | 0 |
| Mmp13 | 1.095488296 | 0 |
| Tmem176a | 1.087765581 | 0 |
| sCol3a1 | 1.082720154 | 1.1707E-254 |