Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 May 21;127(4):637–648. doi: 10.1038/s41416-022-01835-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 4 — a GSEA enrichment plot of CRC samples from TCGA dataset. NES and P-value were calculated in the plot. b Heatmap showing the transcription level of genes in peroxisome pathway. Cells were treated with 6 Gy irradiation. P-value were shown in the plot. c Protein expression of ALDH1L2, NF-κB, pp65, iκBα, CAT, SOD2 and TXN with silencing ALDH1L2 in HCT-15 and HCT 116 cells or forced expression of ALDH1L2 in SW480 and HT-29 cell. β-actin served as a control. d Overlay of histograms by flow cytometry. Mean of DHE in e cells with ALDH1L2 knockdown or f cells with ALDH1L2 overexpressed. g–j Apoptosis of different cell lines and its negative control by flow cytometry. The percentage of cells in all quarters were addressed. Cells were treated with 6 Gy irradiation. k, l Bar graph to show the percentage of apoptosis cells after irradiation. *P < 0.05; **P < 0.01; ***P < 0.001.