Table 2.
Sensitivity analysis results.
| Exposures | Outcomes | Sensitivity analysis methods | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| MR–Egger | Cochran’s Q test | MR–PRESSO | ||||||||
| Egger slope (95% CI) | P–value(Egger slope) | Egger intercept (95% CI) | P–value(Egger intercept) | I2 index | Global test P–value | Outlier–corrected OR (95% CI) | Outlier–corrected P–value | Distortion test P–value | ||
| Body fat mass |
Severe COVID–19 |
1.63 (0.84–3.15) |
0.147 | –0.0002 (–0.012–0.012) |
0.975 | 4.0 | 0.273 | No outlier | — | — |
| Body fat–free mass |
0.74 (0.38–1.45) |
0.378 | 0.009 (–0.001–0.018) |
0.066 | 5.0 | 0.551 | No outlier | — | — | |
| Body fat percentage |
1.79 (0.62–5.14) |
0.282 | 0.001 (–0.013–0.016) |
0.874 | 9.7 | 0.108 | No outlier | — | — | |
| Body mass index | 1.24 (0.65–2.37) |
0.523 | 0.004 (–0.008–0.015) |
0.542 | 1.8 | 0.417 | No outlier | — | — | |
| Body fat mass |
COVID–19 hospitalization |
1.53 (1.17–2.00) |
2.31×10–3 | –0.003 (–0.008–0.002) |
0.264 | 17.3 | 0.004 | 1.3351 (1.3348–1.3353) |
3.98 × 10–3 | 0.881 |
| Body fat–free mass |
1.12 (0.85–1.46) |
0.433 | 0.002 (–0.002–0.006) |
0.302 | 12.3 | 0.174 | No outlier | — | — | |
| Body fat percentage |
1.80 (1.17–2.76) |
8.04×10–3 | –0.003 (–0.009–0.003) |
0.297 | 18.4 | 0.003 | 1.4498 (1.4493–1.4503) |
1.60 × 10–7 | 0.810 | |
| Body mass index | 1.27 (0.99–1.64) |
6.34×10–2 | 0.001 (–0.004–0.005) |
0.812 | 19.5 | 0.001 | 1.3085 (1.3082–1.3088) |
7.09 × 10–9 | 0.864 | |