TABLE 1.
The expression levels of the representative downregulated genes in mTECs and cTECs during aging
| Cell types | Genes | Average expression level (TPM) | |||
|---|---|---|---|---|---|
| Newborn | Adult | Aged | |||
| mTECs | Cell cycle‐related genes or E2F3 targets | Ccna2 | 75.87 | 63.14 | 41.00 |
| Ccnb1 | 93.8 | 86.26 | 60.38 | ||
| Ccnb2 | 73.15 | 56.97 | 41.63 | ||
| Cdk1 | 96.96 | 78.58 | 57.27 | ||
| Cdkn2d | 38.29 | 34.65 | 19.96 | ||
| Ribosomal genes | Rpl23a | 1224.37 | 1002.92 | 760.76 | |
| Rpl10a | 361.87 | 330.44 | 242.68 | ||
| Rps24 | 601.92 | 545.33 | 344.34 | ||
| Rps29 | 1714.98 | 1339.24 | 919.09 | ||
| Rpl9 | 1313.21 | 1105.58 | 726.28 | ||
| cTECs | Cell cycle‐related genes or E2F3 targets | Ccna2 | 53.09 | 41.22 | 5.92 |
| Ccnb1 | 52.71 | 53.66 | 2.13 | ||
| Ccnb2 | 38.14 | 80.92 | 8.57 | ||
| Cdk1 | 64.35 | 21.59 | 2.75 | ||
| Cdkn2d | 39.73 | 45.84 | 33.06 | ||
| Ribosomal genes | Rpl23a | 1267.49 | 827.83 | 626.10 | |
| Rpl10a | 531.99 | 326.59 | 210.05 | ||
| Rps24 | 728.18 | 398.52 | 180.39 | ||
| Rps29 | 1696.40 | 881.87 | 426.52 | ||
| Rpl9 | 2077.67 | 986.22 | 662.24 | ||
Note: According to the RNA‐seq data of Cowan et al. (2019).