Table 3.

Effects of a 180 mg loading dose followed by 90 mg maintenance dose of Brilique® versus Ticaloguard® on % platelet inhibition compared to zero inhibition at baseline of healthy volunteers at different time intervals

Groups	% Platelet inhibition
	1 h after LD	3 h after LD	At day 4, reaching Css	12 h after drug stop	A day after drug stop
Brili group (n = 14)	95.4 (72.9–100)	88.6 (-12.9–100)	89.2 (43.1–98.5)	73.4 (39.5–100)	67.3(34.2–100)
Tica group (n = 15)	87.5 (-2.5–100)	95.2 (-12.8–100)	71.0 (56.2–100)	79.7 (50–92.7)	61.25 (-20.6–86.6)
p-value	0.85	0.911	0.371	0.76	0.315

Data are presented as median (range)

Abbreviation: Brili Brilique®, Tica Ticaloguard®, LD Loading dose, hr Hour, Css Steady state concentration. P: Non-significant by independent-sample Mann–Whitney U test. Negative values indicate resistant cases