Table 1.
Parameter | Groups | Min. | Max. | Mean ± standard deviation | Percent change | p Value |
---|---|---|---|---|---|---|
MMP‐1 | Control | 32,109.00 | 34,955.00 | 33,136.00 ± 1579.68a | 100.00 | .001 |
GZO | 32,453.00 | 33,120.00 | 32,687.67 ± 374.87a | 98.65 | ||
LPS | 37,093.00 | 38,099.00 | 37,582.33 ± 503.56c | 113.42 | ||
LPS and GZO | 33,933.00 | 35,965.00 | 35,163.67 ± 1081.90b | 106.12 | ||
GZO & LPS | 36,854.00 | 39,444.00 | 37,877.33 ± 1377.84c | 114.31 | ||
MMP‐2 | Control | 83,342.00 | 84,815.00 | 83,863.00 ± 825.68a | 100.00 | .003 |
GZO | 81,264.00 | 83,340.00 | 82,611.00 ± 1167.86a | 98.51 | ||
LPS | 85,473.00 | 87,470.00 | 86,518.33 ± 1001.79b | 103.17 | ||
LPS and GZO | 82,324.00 | 84,733.00 | 83,661.33 ± 1226.28a | 99.76 | ||
GZO and LPS | 85,436.00 | 86,755.00 | 86,288.67 ± 739.51b | 102.89 | ||
MMP‐8 | Control | 104.43 | 148.45 | 125.44 ± 22.08ab | 100.00 | .001 |
GZO | 100.43 | 130.54 | 117.80 ± 15.58a | 93.91 | ||
LPS | 175.44 | 197.54 | 184.10 ± 11.80c | 146.76 | ||
LPS and GZO | 142.34 | 155.44 | 147.56 ± 6.94b | 117.63 | ||
GZO and LPS | 166.54 | 185.51 | 173.90 ± 10.17c | 138.63 | ||
MMP‐9 | Control | 60.43 | 69.70 | 65.52 ± 4.70a | 100.00 | .002 |
GZO | 69.43 | 71.32 | 70.43 ± 0.95ab | 107.49 | ||
LPS | 76.43 | 83.23 | 79.07 ± 3.65d | 120.68 | ||
LPS and GZO | 70.32 | 75.54 | 72.43 ± 2.75bc | 110.55 | ||
GZO and LPS | 76.43 | 77.34 | 76.85 ± 0.46cd | 117.29 | ||
IL‐1 β | Control | 16.33 | 18.76 | 17.17 ± 1.38a | 100.00 | .001 |
GZO | 12.06 | 15.77 | 14.38 ± 2.02a | 83.75 | ||
LPS | 21.43 | 26.44 | 23.62 ± 2.56b | 137.56 | ||
LPS and GZO | 19.43 | 25.43 | 22.06 ± 3.07b | 128.47 | ||
GZO and LPS | 21.32 | 23.00 | 22.18 ± 0.84b | 129.13 | ||
IL‐8 | Control | 6047.00 | 6312.00 | 6190.67 ± 133.90ab | 100.00 | .001 |
GZO | 5933.20 | 6127.10 | 6034.87 ± 97.29a | 97.48 | ||
LPS | 6649.30 | 6932.20 | 6824.90 ± 153.32c | 110.24 | ||
LPS and GZO | 6283.90 | 6475.90 | 6351.03 ± 108.24b | 102.59 | ||
GZO and LPS | 6578.40 | 6766.40 | 6680.20 ± 94.97c | 107.91 |
Note: For each parameter, groups with the same letter are not significantly different.
Abbreviations: GZO, ginger Zingiber officinale; IL, interleukin; LPS, lipopolysaccharide; MMP, matrix metalloproteinases.