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. 2022 Aug 3;13:741717. doi: 10.3389/fneur.2022.741717

Table 4.

Outcomes by the severity of injury for TBI cohort (age and sex interaction).

Moderate head injury Severe head injury
n Mortality Unfavorable n Mortality Unfavorable
Male
Neonates and infants 13 0 (0) 1 (7.7) 12 7 (58.3) 10 (83.3)
Toddler 24 0 (0) 2 (8.3) 18 6 (33.3) 10 (55.6)
Early childhood 45 1 (2.2) 4 (8.9) 19 5 (26.3) 9 (47.4)
Middle childhood 43 0 (0) 5 (11.6) 34 9 (26.5) 19 (55.9)
Early adolescence 65 0 (0) 5 (7.7) 69 14 (20.3) 35 (50.7)
p-value 0.6579 0.9683 0.0940 0.3043
Female
Neonates and infants 11 0 (0) 3 (27.3) 0 0 (0) 0 (0)
Toddler 12 0 (0) 2 (16.7) 14 3 (21.4) 7 (50.0)
Early childhood 22 0 (0) 0 (0) 11 1 (9.1) 7 (63.6)
Middle childhood 31 0 (0) 2 (6.5) 24 5 (20.8) 12 (50.0)
Early adolescence 32 0 (0) 3 (9.4) 21 8 (38.1) 14 (66.7)
p-value 0.9683 0.0847 0.3372 0.6268

Severe Head Injury: GCS 3-8, Moderate Head Injury: GCS 9-13.

P-values correspond to the association of outcomes by age for males and females separately for each severity group.