Table 1.
Definition provided for the Thrombotic Event phenotype
| Event type | Confidence level 3 | Confidence level 2 | Confidence level 1 |
|---|---|---|---|
| MYOCARDIAL INFARCTION | ICD-9 code of 410.X or ICD-10 code of I21.X anywhere in the patient's EHR | CL3 + troponin of 0.5 or higher | CL2 + echocardiogram, ECG, or coronary angiogram |
| STROKE | ICD-9 code of 434.11 or ICD-10 code like I63.[0-3]% or ICD-10 code like I63.[5-9]% anywhere in the patient's EHR | CL3 + order for aspirin or clopidogrel + carotid duplex order + echocardiogram order | CL2 + neurology consult order + CT head or MRI brain order |
| DEEP VEIN THROMBOSIS | ICD-9 code of 453.4X or ICD-10 code of I82.4X OR any instance of a DVT sentinel phrase in any note | CL3 + D-Dimer fibrin lab result OR order for anticoagulant | CL2 + LE duplex report with positive DVT sentinel phrase |
| PULMONARY EMBOLISM | ICD-9 code of 415.1X or ICD-10 code of I26.9X anywhere in the patient's EHR | CL3 + new anticoagulant prescription + LE duplex report WITHOUT positive DVT sentinel phrase | CL2 + CT chest or VQ scan order |
| MESENTERIC-SPLANCHNIC THROMBOSIS | ICD-9 code of 557.0X or 444.89 or ICD-10 code of I81.9X/K55.0X/I82.0X/I74.8X anywhere in the patient's EHR | CL3 + new anticoagulant prescription | CL2 + Sonogram order OR CT chest order OR CT abdomen order OR MRI order + D-Dimer fibrin lab result + new order for anticoagulant |
| SUPERFICIAL VEIN THROMBOSIS | ICD-9 code of 453.6X or 451.89 or 453.82 or ICD-10 code of I82.81 or I80.0X or I82.61 | CL2 + new order for anticoagulant | |
| OTHER ARTERIAL THROMBOSIS | ICD-9 code of 444.1X or 444.22 or 453.3X or ICD-10 code of I74.X or I65.1X or I82.3X | CL2 + new order for anticoagulant | |
| PLACENTA THROMBOSIS | ICD-9 code of 663.6X or ICD-10 code of O43.813 | CL2 + new order for anticoagulant | |
| CENTRAL NERVOUS SYSTEM (CNS) THROMBOSIS | ICD-9 code of 437.6X or ICD-10 code of I67.6X | CL2 + new order for anticoagulant | |
| ENDOCARDIAL THROMBOSIS | ICD-9 code of 996.71 or 444.9X or ICD-10 code of I34.8X or I51.3X | CL2 + new order for anticoagulant |
ICD: International Classification of Diseases; CL: confidence level.