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. 2022 Aug 3;12:967000. doi: 10.3389/fonc.2022.967000

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Copyright © 2022 Li, Chen, Zhou, Maimaitirexiati, Yan, Li, Maimaitiyimin, Zhou, Ren, Liu, Mainike, Zhou and Ding

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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LncRNA SCAMP1 overexpression increases invasive and migratory abilities of osteosarcoma cells. (A): Left panel: Transwell invasion assays showed that sh-SCAMP1 transfection reduced invasion of MG63 cells, while SCAMP1 cDNA transfection increased invasion of MG63 cells. Right panel: quantitative data is shown for invasive ability of MG63 cells. (B): Left panel: Transwell invasion assays showed that sh-SCAMP1 transfection and SCAMP1 cDNA transfection modulated invasion of U2OS cells. Right panel: quantitative data is shown for invasion ability of U2OS cells. (C): Wound healing assays showed that sh-SCAMP1 transfection reduced migration of MG63 cells, while SCAMP1 cDNA transfection increased migration of MG63 cells. (D): Wound healing assays showed that sh-SCAMP1 transfection and SCAMP1 cDNA transfection modulated migratory ability of U2OS cells. **p<0.01; ***p<0.001 vs. control group.