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. 2022 Aug 3;12:967000. doi: 10.3389/fonc.2022.967000

Figure 5.

Figure 5

LncRNA SCAMP1 overexpression promotes cell viability and colony formation via miR-26a-5p. (A): CCK8 assays showed that overexpression of lncRNA SCAMP1 abolished miR-26a-5p mimics-mediated inhibition of cell viability in MG63 cells. (B): CCK8 assays showed that inhibition of miR-26a-5p enhanced viability of U2OS cells, which was abrogated by shR-SCAMP1 transfection. (C): Left panel: Colony formation assays showed that in SCAMP1-overexpressing MG63 cells, miR-26a-5p mimics-mediated suppression of colony formation was abolished in MG63 cells. Right panel: quantitative data is shown for colony formation of MG63 cells. (D): Left panel: Colony formation assays showed that in U2OS cells with shR-SCAMP1 transfection, miR-26a-5p-inhibitor-induced colony formation was blocked. Right panel: quantitative data is shown for colony formation of U2OS cells. miR-26a inh: miR-26a inhibitors. **p<0.01; ***p<0.001 vs. control group.