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. 2022 Aug 17;8(1):e12320. doi: 10.1002/trc2.12320

TABLE 2.

Association between having an amyloid PET as part of initial workup and clinical management parameters at follow‐up (n = 352)

Variable Follow‐up time a Tests ordered b DX variability c
Coef (SE) p Coef (SE) p Coef (SE) p
Intercept 6.91 (4.62) 0.13 −2.40 (1.74) 0.48 −2.27 (0.77) 0.003
Amyloid PET ordered* 2.76 (0.85) 0.001 0.17 (0.33) 0.59 0.45 (0.14) 0.001
Age 0.05 (0.05) 0.33 −0.04 (0.02) 0.03 −0.01 (0.01) 0.32
MoCA −0.06 (0.09) 0.48 0.04 (0.04) 0.26 0.02 (0.02) 0.17
Cognitive syndrome ** −0.74 (0.91) 0.41 0.19 (0.36) 0.60 −0.34 (0.16) 0.03
Clinical diagnosis *** 1.76 (0.82) 0.03 −0.84 (0.32) 0.009 −0.44 (0.13) 0.001
Met AUC criteria**** −1.01 (0.88) 0.25 0.81 (0.41) 0.048 0.04 (0.14) 0.80
Variable ChEI prescriptions d Social work referrals c Research referrals c
Coef (SE) p Coef (SE) p Coef (SE) p
Intercept 0.06 (0.10) 0.07 −6.87 (1.79) <0.001 −5.88 (1.76) 0.001
Amyloid PET ordered* 1.24 (0.36) 0.46 0.21 (0.31) 0.50 0.001 (0.32) 0.99
Age 1.05 (0.02) 0.005 0.04 (0.02) 0.05 0.006 (0.02) 0.77
MoCA 0.93 (0.03) 0.01 −0.03 (0.03) 0.33 0.03 (0.03) 0.41
Cognitive syndrome** 2.20 (0.65) 0.008 0.86 (0.31) 0.005 0.17 (0.31) 0.59
Clinical diagnosis *** 0.89 (0.24) 0.67 −0.05 (0.27) 0.86 0.91 (0.34) 0.007
Met AUC criteria**** 1.05 (0.30) 0.87 −0.07 (0.28) 0.78 0.17 (0.31) 0.59

Abbreviations: DX: diagnosis, ChEI: cholinesterase inhibitors, Coef: coefficient, SE: standard error, MoCA: Montreal Cognitive Assessment, AUC: Appropriate Use Criteria

a

linear regression.

b

negative binomial regression.

c

Poisson regression adjusted for difference in follow‐up time.

d

logistic regression.

* Referent: Ordered versus not ordered, ** Referent: Dementia versus mild cognitive impairment, *** Referent: Alzheimer's disease (AD) versus Non‐AD, ****Referent: yes versus no