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Pharmacokinetics Following a Single Oral Dose of Infigratinib 75 mg
| Variable | Subject 1 | Subject 2 | Subject 3 | Subject 4 |
|---|---|---|---|---|
| Pharmacokinetics | ||||
| T1/2 (hour) | 2.73 | 7.75 | 3.02 | 7.62 |
| Tmax (hour) | 2 | 2 | 4 | 6 |
| Cmax (ng/mL) | 28.6 | 176 | 23.8 | 67.9 |
| 24 hour AUC (hour*ng/mL) | 89.68 | 1094.1 | 133.15 | 764.02 |
AUC = area under the curve; Cmax = peak infigratinib concentration; T1/2 = infigratinib half‐life; Tmax = time to maximum infigratinib concentration.
