Table 3.
Chemical name [FL‐no] | Additional data submitted | Reference |
---|---|---|
2‐Phenylcrotonaldehyde [FL‐no: 05.062] | In vitro bacterial reverse mutation assay | BioReliance (2016) |
In vitro MN assay with CREST staining in TK6 cells | BioReliance (2018a) | |
Development and limited validation of a method for the analysis of plasma samples which may contain 2‐phenylcrotonaldehyde | Covance (2014) | |
In vivo MN assay in bone marrow | Covance (2013) | |
In vivo comet assay in duodenum | Covance (2016) | |
In vivo Oral Dose Range Finding Assay in C57BL/6 Mice | BioReliance (2017) | |
In vivo Mutation Assay at the cII Locus in Big Blue® Transgenic C57BL/6 Mice |
BioReliance (2018b) | |
Use levels | Documentation provided to EFSA No. 10 | |
5‐methyl‐2‐phenylhex‐2‐enal [FL‐no: 05.099], 4‐methyl‐2‐phenylpent‐2‐enal [FL‐no: 05.100], 2‐phenylpent‐2‐enal [FL‐no: 05.175], 2‐phenyl‐4‐methyl‐2‐hexenal [FL‐no: 05.222] | Use levels | Documentation provided to EFSA No. 10 |