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. 2022 Aug 17;20(8):e07420. doi: 10.2903/j.efsa.2022.7420

Table 3.

Data evaluated in FGE.216Rev2

Chemical name [FL‐no] Additional data submitted Reference
2‐Phenylcrotonaldehyde [FL‐no: 05.062] In vitro bacterial reverse mutation assay BioReliance (2016)
In vitro MN assay with CREST staining in TK6 cells BioReliance (2018a)
Development and limited validation of a method for the analysis of plasma samples which may contain 2‐phenylcrotonaldehyde Covance (2014)
In vivo MN assay in bone marrow Covance (2013)
In vivo comet assay in duodenum Covance (2016)
In vivo Oral Dose Range Finding Assay in C57BL/6 Mice BioReliance (2017)

In vivo Mutation Assay at the cII Locus in Big Blue® Transgenic

C57BL/6 Mice

BioReliance (2018b)
Use levels Documentation provided to EFSA No. 10
5‐methyl‐2‐phenylhex‐2‐enal [FL‐no: 05.099], 4‐methyl‐2‐phenylpent‐2‐enal [FL‐no: 05.100], 2‐phenylpent‐2‐enal [FL‐no: 05.175], 2‐phenyl‐4‐methyl‐2‐hexenal [FL‐no: 05.222] Use levels Documentation provided to EFSA No. 10