. 2022 Aug 17;20(8):e07420. doi: 10.2903/j.efsa.2022.7420

Table D.2.

Summary of in vivo genotoxicity data on 2‐phenylcrotonaldehyde [FL‐no: 05.062] of subgroup 3.3

Chemical Name [FL‐no]	Test system in vivo	Test object Route	Doses	Result	Reference	Comments
2‐Phenylcrotonaldehyde [FL‐no: 05.062]	Micronucleus assay in bone marrow	Rat Gavage	70, 350 and 700 mg/kg bw per day	Negative	Henderson (2013)	The study complies with OECD TG 474. No clear evidence of bone marrow exposure, therefore the test is inconclusive.

Chemical Name

[FL‐no]

Test system in vivo

Test object

Route

Doses

Result

Reference

Comments

2‐Phenylcrotonaldehyde

[FL‐no: 05.062]

Micronucleus assay in bone marrow

Rat

Gavage

70, 350 and 700

mg/kg bw per day

Negative

Henderson (2013)

The study complies with OECD TG 474. No clear evidence of bone marrow exposure, therefore the test is inconclusive.