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. 2022 Jan 13;102(4):pzac005. doi: 10.1093/ptj/pzac005

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© The Author(s) 2022. Published by Oxford University Press on behalf of Faculty of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

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Fatigue and postexertional malaise (PEM). Rain cloud plot⁵² of fatigue (Functional Assessment of Chronic Illness Therapy–Fatigue Scale [FACIT-F] score, with a lower score representing more severe fatigue) in people with PEM, identified using step 2 scoring criteria for the DePaul Symptom Questionnaire–Post-Exertional Malaise (DSQ-PEM). Participants with PEM reported more severe fatigue (P_Holm [Holm-Bonferroni adjusted P value] = .011). As a crude marker of severity, the dashed line shows the threshold score of clinical relevance in oncology, recommended for the diagnosis of cancer-related fatigue.