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. 2022 Feb 15:hcac040. doi: 10.1093/qjmed/hcac040

Table 1.

Basic characteristics of the included systematic reviews

Serial number Authors Title Country No of studies included Types of studies included Total population
1 Chen et al., Oct 2012114 Low vitamin D levels do not aggravate COVID-19 risk or death, and vitamin D supplementation does not improve outcomes in hospitalized patients with COVID-19: A meta-analysis and GRADE assessment of cohort studies and RCTs China 13 Cohort studies = 11, Randomized control Trials = 2 5 36 418
2 Grove et al., May 202115 Association between vitamin D supplementation or serum vitamin D level and susceptibility to SARS-CoV-2 infection or COVID-19 including clinical course, morbidity and mortality outcomes? A systematic review UK 4 Cross-sectional study = 1, retrospective cohort study = 1, ecological country study = 1, case-control survey = 1 2042
3 Hariyanto et al., June 202116 Vitamin D supplementation and Covid-19 outcomes: A systematic review, meta-analysis and meta-regression Indonesia 11 Retrospective cohort studies = 4, Open-label randomized clinical trial = 1, Prospective cohort studies = 2, Cross-sectional studies = 3, double-blind randomized clinical trial = 1 2265
4 Nikniaz et al., Jan 202117 The impact of vitamin D supplementation on mortality rate and clinical outcomes of COVID-19 patients: A systematic review and meta-analysis Iran 4 Randomized control trials = 2, Quasi Experimental trials = 2 259
5 Pal et al., June 202118 Vitamin D supplementation and clinical outcomes in COVID 19: a systematic review and meta-analysis India 13 Randomized control trials = 3, Observational studies = 10 2933
6 Rawat et al., June 202119 Vitamin D supplementation and COVID-19 treatment: A systematic review and meta-analysis India 5 Randomized control trials = 3, Quasi experimental studies = 2 467
7 Shah et al., May 202120 Vitamin D supplementation, COVID-19 and disease severity: a meta-analysis India 3 Randomized control trials = 2, retrospective case-control study = 1 532
8 Stroehlein et al., May 202121 Vitamin D supplementation for the treatment of COVID‐19: a living systematic review Germany 3 Randomized control trials = 3 356
9 Tentolouris et al., Dec 202122 The effect of vitamin D supplementation on mortality and intensive care unit admission of COVID-19 patients. A systematic review, meta-analysis and meta-regression Greece 10 Randomized control trials = 2, non-randomized trials = 8 2078
10 Vaughan et al., Oct 202123 Changes in 25‐hydroxyvitamin D levels post‐vitamin D supplementation in people of Black and Asian ethnicities and its implications during COVID‐19 pandemic: A systematic review UK 8 Randomized control trials = 8 1108