TABLE 3.
Relevant properties and response to mitomycin C in selected pneumococcal isolates
| Strain | Serogroup or type | PFGE patterna | lytA (kb)c | recA (kb)c | Pen MIC (μg/ml)d | Resistancee | Mitomycin induction |
|---|---|---|---|---|---|---|---|
| MA42 | 19 | 2(2) | 145, 90, 70 | 90 | 16 | E, T, Cm | Yes |
| MA47 | 19 | 18(11) | 280, 90–80 | 90 | 16 | E, T, Cm | Yes |
| MA49 | 19 | 18(13) | 190, 160, 90 | 90 | 16 | E, T, Cm | Yes |
| MA62 | 19 | 2(8) | 245, 90, 70 | 90 | 16 | E, T, Cm | Yes |
| MA75 | 19 | 18(9) | 280, 90 | 90 | 8 | E, T, Cm | Yes |
| MA81 | 22 | 27 | 260, 80 | 80 | 0.5 | T, Cm | No |
| SVMC12 | NDb | 11 | 200, 90 | ND | 0.3 | E, T | Yes |
| SVMC17 | 23F | 1(2) | 90, 30 | ND | 6 | E, T, Cm | No |
| SVMC23 | 16 | 16 | 90, 85 | ND | S | — | No |
| SVMC27 | 23 | 8 | 225, 85 | ND | 1 | T | Yes |
| SVMC28 | 23 | 17 | 95, 60 | ND | S | — | Yes |
| SVMC31 | 9 | 5(2) | 255, 95 | ND | 2 | T | No |
| SVMC32 | 14 | 6 | 115 | ND | 2 | E, T | No |
| SVMC33 | 18 | 3 | 225, 85, 70 | ND | S | — | Yes |
| SVMC35 | 23F | 1(2) | 90, 30 | ND | 2 | E, T, Cm | No |
| SVMC36 | 3 | 1(10) | 90, 30 | ND | 3 | E, T, Cm | No |
| SVMC52 | 19 | 23 | 95, 85 | ND | S | — | Yes |
| SVMC54 | 6 | 13 | 80, 60 | ND | 0.1 | E, T | Yes |
a
The pattern numbers given are arbitrary. The first number denotes the PFGE pattern type (defined by the number and size of the bands). Patterns that differ by fewer than four fragments were classified as subtypes and assigned a different number in parentheses.
b
ND, not determined.
c
Molecular sizes of fragments hybridizing to probes for the gene indicated.
d
Penicillin MIC. S, sensitive.
e
E, erythromycin; T, tetracycline; Cm, chloramphenicol. The dash indicates susceptibility.