Table 1.
Patient characteristics per study
| Reference | Patients (n) | Male (%) | Age (years)a | BMI (kg/m²)a | Time after transplantation (years)a | >2 immunosuppressants (%) | Subjects on MMF/MPA (%) | Serum creatinine, median (IQR) | Lymphocyte count |
|---|---|---|---|---|---|---|---|---|---|
| Boyarsky et al. [15] | 658 | 41 | 18–39: 17% 40–59: 31% ≥60: 51% |
NA | <3: 28% 3–6: 21% 7–11: 22% ≥12: 29% |
NA | 66a | NA | NA |
| Dębska-Ślizień et al. [16] | 142 | 58 | Median 54 (43–63) | 25 (22.55–28.37) | Median 8 (IQR 3.5–15) | 73 | 79 | 1.35 (1.12–1.7) | NA |
| Hallett et al. [17] | 237 | 46 | 62 (46–69) | 25.6 (21.9–29.7) | 5.1 (2.5–11.0) | 34 | 62 | NA | NA |
| Narasimhan et al. [18] | 73 | 64 | 65 (53.5–69.5) | NA | 3.3 (1.6–5.3) | NA | 99 b | NA | NA |
| Strauss et al. [19] | 161 | 43 | 64 (48–69) | 26.0 (23.0–30.5) | 6.9 (2.9–15.0) | NA | 35 | NA | NA |
| Stumpf et al. [20] | 368 | 65 | 57.3 ± 13.7 | 26.4 ± 4.8 | 9.9 ± 6.8 | 35 | 76 | NA | NA |
| Wijtvliet et al. [21] | 133 | 59 | NA | NA | NA | NA | 53 | NA | NA |
| Yi et al. [14] | 105 | 62 | 57.0 (46.0–64.0) | NA | 1.0 (0.0–3.0) | NA | 81 | NA | NA |
NA, not available.
Frequencies were calculated of those with available data.
aValues presented as percentage, median (IQR) or mean ± standard deviation.
bAlso included azathioprine.