Table 2.
Overview of Antigens Used in MULTICOV-AB and RBDCoV-ACE2 Assays
| Antigen | Manufacturer | Category Number | Mutations Covered |
|---|---|---|---|
| Spike WT (B.1) | NMI | … | … |
| RBD WT (B.1) | NMI | … | … |
| S1 domain WT (B.1) | NMI | … | … |
| S2 domain WT (B.1) | Sino Biological | 40590-V08B | … |
| Nucleocapsid WT (B.1) | Aalto Bioreagents | 6404-b | … |
| RBD Alpha (B.1.1.7) | NMI | … | N501Y |
| RBD Beta (B.1.351) | NMI | … | K417N, E484K, N501Y |
| RBD Gamma (P1) | NMI | … | K417T, E484K, N501Y |
| RBD Delta (B.1.617.2) | NMI | … | L452R, T478K |
| RBD Omicron (B.1.529/BA.1) | Sino Biological | 40592-V08H121 | G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H |
| Spike Omicron (B.1.1.529/BA.1) | Sino Biological | 40589-V08H26 | A67V, del HV69/70, T95I, G142D, del VYY 143-145, del N211, L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, H655Y, N679K, P681H, N764K, D796Y, F817P, N856K, A892P, A899P, A942P, Q954H, N969K, L981F, K986P, V987P |
| RBD Omicron (B.1.1.529/BA.2) | Sino Biological | 40592-V08H123 | G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H |
| Nucleocapsid Omicron (B.1.1.529/BA.2) | Sino Biological | 40588-V07E35 | P13L, del ERS 31-33, R203K, G204R, S413R |
| RBD Lambda (C.37) | NMI | … | L452Q, F490S |
| RBD Mu (B.1.621) | NMI | … | R346K, E484K, N501Y |