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. 2022 Jun 20:jiac250. doi: 10.1093/infdis/jiac250

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© The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

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Figure 1. — Analysis of antibody response induced by Omicron breakthrough infection. A, Titers of serum IgG anti-spike antibodies were analyzed by ELISA. The geometric means with 95% CIs are shown. B, Serum neutralizing titers against the ancestral variant B.1 and Omicron (BA.1) were analyzed using isolated variants. The geometric means with 95% CIs are shown. C, Paired B.1 and BA.1 neutralization titters for each sample. A and B, Kruskal-Wallis test and Dunn test for multiple comparisons were used. C, Wilcoxon pair-matched test was used. *P = .05, **P = .005, ***P = .0005, ****P = .0001. Dotted lines in panels A, B and C represents detection limits. Abbreviations: CI, confidence interval; ELISA, enzyme-linked immunosorbent assay; IgG, immunoglobulin G; nAbs, neutralizing antibodies.