Table 2.
Published sensitivity and specificity of RSV tests by assay technology in all included studies.
| RSV tests with analytical time ≤30 min (n = 88) | RSV tests with analytical time >30 min (n = 45) | ||
|---|---|---|---|
| Method | Antigen | Molecular | Molecular |
| Subrecords, n (%) | 61 (69.3) | 27 (30.7) | 41 (91.1)a |
| Overall | |||
| Sensitivity, % | 25.7–100 | 66.7–100 | 62.5–100 |
| Specificity, % | 80.3–100 | 94.3–100 | 77.0–100 |
| Age | |||
| <18 years | |||
| Sensitivity, % | 25.7–97.6 | 84.3–100 | 74.3–100 |
| Specificity, % | 80.3–100 | 94.3–100 | 97.8–100 |
| ≥18 yearsb | |||
| Sensitivity, % | — | — | 62.5–100 |
| Specificity, % | — | — | 98.9–100 |
| Mixed age | |||
| Sensitivity, % | 57.5–100 | 77.8–100 | 63.2–100 |
| Specificity, % | 91.8–100 | 94.7–100 | 77.0–100 |
| Setting | |||
| Inpatient | |||
| Sensitivity, % | 25.7–95.2 | 98.1–100 | 80.4–100 |
| Specificity, % | 80.3–100 | 94.3–99.4 | 91.5–100 |
| Emergency department/outpatient | |||
| Sensitivity, % | 67.8–97.6 | 93–100 | 62.5–100 |
| Specificity, % | 97.6–99.6 | 96–100 | 97.8–100 |
a
The mariPOC Respi test (n = 4 subrecords) was included in the RSV tests with analytical time >30 min category as the final result is available after 2 h. The sensitivity and specificity values were not included in the table as there were insufficient data to produce a range of sensitivity or specificity values for relevant patient and setting characteristics.
b
Only 1 study assessed an RSV test with analytical time ≤30 min in an adult-only (≥18 years) population; therefore, it was not possible to produce a range of sensitivity or specificity values.