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. 2022 Jul 25;226(9):1577–1587. doi: 10.1093/infdis/jiac225

Figure 3.

Figure 3.

A and B, Serum or plasma nucleocapsid plotted against time since diagnosis (A) and symptom onset (B). Samples without antigen detected are shown stacked on the horizontal axis. Four samples with antigenemia beyond 41 days are listed in the box and 93 samples without antigenemia between 41 and 351 days after earliest diagnosis are not shown. C, Serum or plasma nucleocapsid in patients whose COVID-19 course was described as asymptomatic in clinical records. The x-axis reflects time between first known positive respiratory test and the day the blood sample used in our analysis was collected. Shape and shading of each symbol classify serological status of asymptomatic patients. D, Serum or plasma nucleocapsid for individuals with positive nasopharyngeal RT-PCR on the same day as blood sample collection. Shape and shading of each symbol classify clinical status of patients. Abbreviations: COVID-19, coronavirus disease 2019; N, nucleocapsid; RBD, receptor-binding domain; RT-PCR, reverse transcription polymerase chain reaction; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.