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. 2022 Aug 6:jiac304. doi: 10.1093/infdis/jiac304

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© The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

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Figure 2. — Children with multisystem inflammatory syndrome in children (MIS-C) have elevated chemokine responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigens. Whole blood from children with MIS-C (n = 15), coronavirus disease 2019 (COVID-19) (n = 10), and other infectious diseases (Inf) (n = 10) were stimulated with medium alone, SARS-CoV-2 spike receptor-binding domain (S-RBD), SARS-CoV-2 irradiated cell lysate (ICL), and Mycobacterium tuberculosis whole cell lysate (Mtb WCL) for 12 hours. Levels of CC (A) and CXC (B) chemokines were measured by multiplex assays. Each circle represents a single individual and the bars represent the geometric mean values. P values were calculated using the Kruskal–Wallis test with Dunn multiple comparisons.