Table 1.
Demographic Characteristics and Hematological Parameters of the Study Population
| Characteristic | MIS-C | Acute COVID-19 (n = 10) |
Other Infectious Diseases (n = 10) |
|
|---|---|---|---|---|
| During MIS-C (n = 15) | After MIS-C (n = 8) |
|||
| Age, y, median (range) | 4.5 (1–13) | 9 (3–12) | 2 (1–13) | 3 (1–10) |
| Male sex, No. (%) | 9 (60) | 7 (63.6) | 5 (50) | 3 (30) |
| RT-PCR positive, No. (%) | 2 (1.3) | NA | 7 (70) | 0 |
| Serology IgG positive, No. (%) | 13 (86.6) | 4 (36.36) | 1 (10) | 3 (30) |
| CRP <3 mg/L, No. (%) | 5 (50) | 0 (0) | 7 (46.6) | 2 (20) |
| WBC count, 103 cells/µL, GM (range) | 8.16 (3.65–13.29) | 7.27 (5.35–9.51) | 5.71 (4.41–8.19) | 11.28 (5.13–29.83) |
| Hemoglobin, g/dL, GM (range) | 10.15 (6–16.1) | 12.17 (10.94–13.14) | 10.68 (8.3–13.09) | 10.9 (7.39–14.33) |
| Lymphocyte, %, median (range) | 39.53 (4.85–63.95) | 44.97 (36.3–62.99) | 71.05 (12.45–80.4) | 57.65 (14.13–63.22) |
| Neutrophils, %, median (range) | 76.50 (32–89) | 39.76 (23.28–53.3) | 26.55 (10.59–82.14) | 31.13 (22.97–83.25) |
| Platelets (200–450) ×109/L, median (range) | 267.3 (84.8–355.5) | 295.54 (151.6–433) | 264.55 (174.8–367.9) | 339.3 (28.7–1044.6) |
| Sodium (135–145 mmol/L), median (range) | 132.5 (124–137) | … | NA | NA |
| Ferritin, ng/mL, median (range) | 762.5 (306.1–5377) | … | NA | NA |
| Duration of stay, d, median (range) | 7.5 (2–13) | NA | 4 (2–6) | 6.5 (3–7) |
| Dengue serology or NS1 positivity | … | … | … | 4 |
| Scrub typhus (IgM) | … | … | … | 4 |
| Enteric fever (culture confirmed) | … | … | … | 2 |
Abbreviations: COVID-19, coronavirus disease 2019; CRP, C-reactive protein; GM, geometric mean; IgG, immunoglobulin G; IgM, immunoglobulin M; MIS-C, multisystem inflammatory syndrome in children; NA, not applicable; RT-PCR, reverse-transcription polymerase chain reaction.