Table 2.
Follow-up Radiographic assessment of APM and comparator groups in cohort studies and RCTs.
| Author, year | Sample sizea/design | Follow-up range (years) | Baseline radiographic status | Primary outcome variable | Findings | P-Value | Conclusion |
|---|---|---|---|---|---|---|---|
| Fauno, 1992 [37] | 136/Cohort | 8–12 | Not reported | ≥1 pt Fairbank change | APM: 53% Control knee: 22% |
P < 0.001 | APM associated with increased Fairbanks changes |
| Herrlin, 2012 [13] | 88/RCT | 5 | Ahlback grade ≤1 | ≥1 pt Ahlback change | APM: 4.7% PT-only: 4.4% |
P = 1.0c | APM not associated with osteoarthritic changes |
| Yim, 2013 [16] | 102/RCT | 2 | KL grade ≤1 | KL grade ≥2 | APM: 4% Non-operative: 5.8% |
P = 0.44 | Did not find differences in OA changes between groups |
| Hulet, 2015 [39] | 89/Cohort | 19–25 | IKDC§ grade ≤4 | OA on objective IKDC score (B, D)b | APM: 45% Contralateral: 19% |
P = 0.0004c | APM associated with OA changes. |
| Sihvonen, 2020 [6] | 146/RCT | 5 | KL ≤ 2 | ≥1 kL grade change | APM: 72% Sham: 60% |
P = 0.16c | APM associated with greater risk radiographic OA than sham |
| Sonesson, 2020 [11] | 146/RCT | 5 | Ahlback grade 0 | KL grade ≥2 | APM + Exercise: 60% Exercise-only: 37% | P = 0.06 | Greater incidence OA changes, though P > 0.05. |
KL = Kellgren-Lawrence grades 0–4 scale of knee OA presence 0 = absence of osteoarthritic changes, 1 = doubtful/possible, 2 = minimal, 3 = moderate, 4 = severe [54].
Ahlback grades 0–5, 0 = no radiographic OA changes, 1 = joint space narrowing (<3 mm), 2 = obliterated or partially obliterated joint space, 3 = minor bone attrition (<5 mm), 4 = moderate bone attrition (5–15 mm), 5 = severe bone attrition (>15 mm) [55].
APM = arthroscopic partial meniscectomy; IKDC = International Knee Documentation Committee, ROA = radiographic knee osteoarthritis.
= Sample size with available radiograph at follow-up.
= Participants were categorized into grades A (healthy), B (asymptomatic with ROA), C (symptomatic, no ROA), and D (symptomatic, with ROA) using the objective §IKDC score with grades 0–3, 0 = normal, 1 = articular modeling, 2 = joint space narrowing (≤50%), 3 = joint space narrowing (≥50%) [39].
= We calculated crude p-values for these results as they were unreported in the original paper.