Table 2.

Association between SGLT2i, GLP1-RA or DPP-4i use, and risk of incident COVID-19 outcome, i.e. presence of a hospitalization with confirmed COVID-19 as main diagnosis in the National Patient Registry or as confirmed COVID-19 as underlying cause of death in the Cause of Death Registry

Model	SGLT2i no	SGLT2i yes	P-value	GLP1-RA no	GLP1-RA yes	P-value	DPP-4i no	DPP-4i yes	P-value
Matched, n (%) event	864 (2.2)	962 (2.5)		862 (2.5)	906 (2.7)		1485 (2.8)	1639 (3.1)
RR (95% CI)	ref	1.11 (1.02–1.22)	0.020	ref	1.05 (0.96–1.15)	0.289	ref	1.10 (1.03–1.18)	0.005
Competing risk HR (95% CI)	ref	1.11 (1.02–1.22)	0.021	ref	1.05 (0.96–1.15)	0.290	ref	1.11 (1.03–1.19)	0.005
All patients, n (%) event	8575 (2.8)	963 (2.5)		8631 (2.8)	907 (2.7)		7899 (2.7)	1639 (3.1)
Crude RR (95% CI)	ref	0.88 (0.82–0.93)	<0.001	ref	0.95 (0.89–1.02)	0.140	ref	1.14 (1.08–1.20)	<0.001
Adjusted RR (95% CI)	ref	1.09 (1.02–1.16)	0.017	ref	1.10 (1.02–1.18)	0.010	ref	1.15 (1.09–1.22)	<0.001