Figure 2.

Schematic overview of the proposed effect of C1q deficiency on human disease based on the outcome of studies performed in murine disease models. Beneficial effects are colored in turquoise, detrimental in ocher, and outcomes without general trend or with ambiguous results in grey. The size of the colored area and the underlying pie chart illustrate the number of studies performed in the respective area. MS multiple sclerosis, I/R ischemia and reperfusion, SLE systemic lupus erythematosus.