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Macrophage in early AMD. Oval-shape macrophage in the intercapillary zone next to the elastic layer of the BM. The narrow cytoplasm is poor in cytoplasmic processes, it contains two round-shape mitochondria with confluent electrodense cristae and several endosomes. One of the mitochondria forms contact site with a lysosome (black arrow). The nuclear membrane is dilated nearly all round the nucleus (white arrows). Seventy-two years; male; ×22,000; bar: 1 μm
