Figure 4.

Lip1 pretreatment abolished Lys-mediated suppression of CRC cells. Prior to the addition of 30 M of Lys, HCT116 and SW480 cells were pretreated with Lip1 at a concentration of 200 nM for six hours. The CCK-8 test and the clonogenic assay were used to determine the level of cell viability (b) and survival (c), respectively, 24 hours after Lys was administered. The Transwell test was used to ascertain the level of motility present in CRC cells (c, d). The data are either pictures that are typical of the whole or are given as the mean plus the standard deviation. ^∗P < 0.05, ^∗∗P < 0.01.