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. 2022 Aug 3;9:937412. doi: 10.3389/fcvm.2022.937412

Table 3.

Combined models of BPs and RHR for all-cause mortality.

Combined models of SBP and RHR for all-cause mortality; N = 2013, 165 deaths
Baseline SBP (per 10 mmHg increase) Baseline RHR (per 10 bpm increase)
HR (95% CI) p -Value HR (95% CI) p -Value
Model 1. + Age, Sex, BMI, Diabetes, CAD, PH, AF, NYHAc, eGFR 0.89 (0.826–0.958) 0.002 1.09 (1.018–1.171) 0.014
Model 2. Model 1 + Severe TR, LVEF, LVEDDi 0.90 (0.833–0.969) 0.005 1.09 (1.013–1.170) 0.020
Model 3. Model 1 + β blocker, Diuretic 0.89 (0.822–0.955) 0.002 1.08 (1.007–1.160) 0.031
Model 4. Model 1 + Hb, Alb, Tbil 0.91 (0.841–0.975) 0.009 1.10 (1.023–1.180) 0.010
Model 5. Model 1 + Etiology 0.86 (0.792–0.934) <0.001 1.11 (1.033–1.202) 0.005
Combined models of DBP and RHR for all-cause mortality; N = 2,013, 165 deaths
Baseline DBP (per 10 mmHg increase) Baseline RHR (per 10 bpm increase)
HR (95% CI) p -Value HR (95% CI) p -Value
Model 1. + Age, Sex, BMI, Diabetes, CAD, PH, AF, NYHAc, eGFR 0.76 (0.671–0.861) <0.001 1.15 (1.070–1.232) <0.001
Model 2. Model 1 + Severe TR, LVEF, LVEDDi 0.76 (0.667–0.859) <0.001 1.14 (1.064–1.230) <0.001
Model 3. Model 1 + β blocker, Diuretic 0.76 (0.672–0.860) <0.001 1.14 (1.060–1.222) <0.001
Model 4. Model 1 + Hb, Alb, Tbil 0.80 (0.705–0.912) 0.001 1.14 (1.062–1.227) <0.001
Model 5. Model 1 + Etiology 0.72 (0.627–0.826) <0.001 1.18 (1.096–1.273) <0.001

AF, atrial fibrillation; Alb, albumin; BMI, body mass index; CAD, coronary heart disease; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; Hb, hemoglobin; LVEDDi, indexed left ventricular end-diastolic dimension; LVEF, left ventricular ejection fraction; PH, pulmonary hypertension; RHR, resting heart rate; SBP, systolic blood pressure; Tbil, total bilirubin; TR, tricuspid regurgitation.