TABLE 2.
Characteristics comparisons between EGFR muted patients with and without T790M
| Characteristic | EGFR mutated patients (n = 130) | ||
|---|---|---|---|
| T790M‐negative (n = 97) | T790M‐positive (n = 33) | p‐value | |
| Gender | 0.761 | ||
| Male | 47 (73.4) | 17 (26.6) | |
| Female | 50 (75.8) | 16 (24.2) | |
| Age | |||
| Median | 64 | 56 | |
| Range | 33–87 | 34–83 | |
| NSE | 0.642 | ||
| Elevated | 66 (75.9) | 21 (24.1) | |
| Normal | 31 (72.1) | 12 (27.9) | |
| CEA | <0.01 | ||
| Elevated | 66 (68.8) | 30 (31.3) | |
| Normal | 31 (91.2) | 3 (8.8) | |
| CA125 | 0.551 | ||
| Elevated | 56 (72.7) | 21 (27.3) | |
| Normal | 41 (77.4) | 12 (22.6) | |
| CA153 | 0.316 | ||
| Elevated | 52 (71.2) | 21 (28.8) | |
| Normal | 45 (78.9) | 12 (21.1) | |
| CYFRA21‐1 | 0.508 | ||
| Elevated | 76 (76) | 24 (24) | |
| Normal | 21 (70) | 9 (30) | |
| SCC | 0.056 | ||
| Elevated | 24 (88.9) | 3 (11.1) | |
| Normal | 73 (70.9) | 30 (29.1) | |
| Pathology | |||
| Adenocarcinoma | 92 (70.8) | 32 (24.6) | |
| Squamous carcinoma | 2 (1.5) | 0 (0) | |
| Adenosquamous carcinoma | 0 (0) | 0 (0) | |
| SCLC | 1(0.8) | 0 (0) | |
| Others a | 2 (1.5) | 1 (0.8) | |
| Gross | 97 (74.6) | 33 (25.4) | |
Values presented are n (%) unless otherwise noted.
a
Others include epitheliomatoid carcinoma, complex small cell carcinoma, and other unknown pathological types of lung cancer.