Table 2.
Positive rate of our CRC diagnostic model for clean healthy individuals, healthy individuals with colorectal polyps, advanced adenoma patients, and patients with CRC in different stages of CRC progression (stage and T classification)
| Group | n | Positive rate (%) |
| Clean healthy individuals | 317 | 10.7 (7.3–14.2) |
| Healthy individuals with polyps | 165 | 13.3 (8.5–18.8) |
| Advanced adenoma patients | 75 | 12.0 (5.3–20.0) |
| CRC patients | ||
| Stage | ||
| 0 | 68 | 19.1 (10.3–29.4) |
| I | 107 | 45.8 (36.4–55.1) |
| II | 77 | 66.2 (55.8–76.6) |
| III | 130 | 63.1 (54.6–71.5) |
| IV | 44 | 68.2 (54.5–81.8) |
| p = 7.99 × 10–10 | ||
| T classification | ||
| Tis | 68 | 19.1 (10.3–29.4) |
| T1 | 77 | 48.1 (36.4–59.7) |
| T2 | 60 | 46.7 (33.3–60.0) |
| T3 | 166 | 66.3 (59.0–73.5) |
| T4 | 55 | 67.3 (54.5–80.0) |
| p = 6.88 × 10–11 | ||
Ranges in parentheses are 95% confidence intervals with 10,000 bootstrap replicates. Statistical significance was determined with the Cochran–Armitage test for trends in proportions. p values < 0.05 were considered significant.