Table 2.

Results of the conditional analysis on MI and coronary atherosclerosis.

Phenotype	SNPID [chr:position:ref:alt] (rsid)	Most severe consequence	Original GWAS results		Conditional results
			OR [CI]	p-value	OR [CI]	p-value
Coronary atherosclerosis	chr15:88901702:C:CTGT (rs534125149)	Inframe insertion	0.75 [0.71–0.81]	2.63 × 10−16	0.75 [0.70–0.80]a	7.68 × 10−15a
	chr15:88899813:T:G (rs201988637)	Splice acceptor variant	0.72 [0.63–0.83]	7.94 × 10−6	0.73 [0.64–0.85]b	1.99 × 10−5b
Myocardial infarction, strict	chr15:88901702:C:CTGT (rs534125149)	Inframe insertion	0.74 [0.68–0.81]	1.95 × 10−11	0.79 [0.73–0.85]a	1.92 × 10−10a
	chr15:88899813:T:G (rs201988637)	Splice acceptor variant	0.69 [0.58–0.83]	9.62 × 10−5	0.71 [0.59–0.85]b	4.03 × 10−4b

This table present the conditional analysis results for coronary atherosclerosis and MI (strict definition, only primary diagnoses accepted) where the association has been conditioned on rs534125149 and rs201988637, separately.

^aConditional on rs201988637.

^bConditional on rs534125149.