Table 4.

Differentially expressed genes of hub genes in U87 glioblastoma cells upon treatment of CCA-1.1.

No	Gene symbol	Ref seq	Gene name	Log FC	p value
1	EGFR	NM_001346900.2	Epidermal growth factor receptor (EGFR), transcript variant 8, mRNA	8.83688311	1.03E-05
		NM_001346941.2	Epidermal growth factor receptor (EGFR), transcript variant EGFRvIII, mRNA	−6.111141843	0.00063995
		NM_001346898.2	Epidermal growth factor receptor (EGFR), transcript variant 6, mRNA	−2.651710224	0.10586144
		NR_047551.1	EGFR antisense RNA 1 (EGFR-AS1), long non-coding RNA	2.325569699	0.30560263
		NM_201283.2	Epidermal growth factor receptor (EGFR), transcript variant 3, mRNA	−0.969886184	0.5118575
		NM_001346899.2	Epidermal growth factor receptor (EGFR), transcript variant 7, mRNA	−0.816340926	0.56093641
		XM_047419953.1	Epidermal growth factor receptor (EGFR), transcript variant X2, mRNA	−0.777241106	0.59354503
		NM_001346897.2	Epidermal growth factor receptor (EGFR), transcript variant 5, mRNA	0.155644698	1
2	TP53	not found	Not found	Not found	Not found
3	AKT1	NM_001014431.2	AKT serine/threonine kinase 1 (AKT1), transcript variant 3, mRNA	−0.173979481	0.8970585
4	ALB	not found	Not found	Not found	Not found
5	SRC	not found	Not found	Not found	Not found
6	TNF	NM_016292.3	TNF receptor associated protein 1 (TRAP1), transcript variant 1, mRNA; nuclear gene for mitochondrial product	0.095069258	0.94426958
7	CASP3	not found	Not found	Not found	Not found
8	MAPK1	NM_138957.3	Mitogen-activated protein kinase 1 (MAPK1), transcript variant 2, mRNA	0.095103156	0.94434009
9	HSP90AA1	NM_005348.4	Heat shock protein 90 alpha family class A member 1 (HSP90AA1), transcript variant 2, mRNA	−0.088807883	0.94722009
10	MAPK8	NM_001323330.2	Mitogen-activated protein kinase 8 (MAPK8), transcript variant 16, mRNA	−0.03700038	1

Significant values are in bold.