Figure 1.

Differential expression and co-expression analysis of 24 TSPAN genes

(A) Gene expression in pan-cancer.

(B) The heatmap shows expression levels of TSPAN genes among 33 cancer types; the gradation of color represents log2 Fold Change (log FC) value.

(C and D) The differential expression of TSPAN1 and TSPAN15 between tumor and adjacent normal tissue in 23 cancer types. (Triple “∗” represent p < 0.001, double “∗” represent p < 0.01 and single “∗” represent p < 0.05).

(E) Co-expression heatmap demonstrates co-expression relations of TSPAN genes. The correlation coefficients are shown in the boxes.