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. 2022 Aug 17;12:13970. doi: 10.1038/s41598-022-18232-6

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Genomic location and specificity of the unique differentially methylated regions in ASD with 16p11.2 deletion. Genomic location on XK related 6 (XKR6) (a), Zinc Finger Protein 107 (ZNF107) (b) and Myeloma overexpressed 2 (MYEOV2) (c): blue line represents hypomethylation, red line represents hypermethylation. The receiver operating characteristic (ROC) analysis of the unique differentially methylated regions of ASD with 16p11.2 deletion (n = 7) was performed against non-ASD (n = 48) and ASD with CHD8 variants (n = 15). Specificity and sensitivity of the unique differentially methylated regions for XKR6 (d), ZNF107 (e) and MYEOV2 (f).