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. 2022 Aug 17;13(8):716. doi: 10.1038/s41419-022-05160-6

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A Immunohistological assessment of myofiber cross-sectional area via laminin staining (Laminin, upper row), and hematoxylin and eosin staining (H&E, lower row) to assess fiber integrity indicated central nuclei, regenerating fibers, macrophage infiltration, and fiber death. B Muscle mass in the DDp53 tibialis anterior was significantly reduced three weeks after electroporation. C Fiber cross sectional area was significantly reduced in DDp53 three weeks after electroporation. D Fiber diameter was significantly reduced in DDp53 three weeks after electroporation. n = 6 to 12, * indicates a p-value of <0.05, **** indicates a p-value of <0.0001.