Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Aug 17;13(8):716. doi: 10.1038/s41419-022-05160-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 4 — A Total IRS1 protein levels did not change with DDp53 electroporation. B Glucose transporter GLUT4 protein levels did not change with DDp53 electroporation. C Mitochondrial complex I (NDUFB8) protein levels were significantly decreased with DDp53 in tibialis anterior muscle. D Mitochondrial complex II (SDHB) protein levels were unchanged with DDp53. E Mitochondrial complex V (ATP5A) protein levels were significantly reduced after DDp53 electroporation compared to control muscle. F GAPDH protein levels were significantly reduced with DDp53 compared to the control leg. Individual data points represent the results from a single animal. Squares represent the leg that was electroporated with DDp53, circles the contralateral control leg of the same animals. Western blot images show three representative bands from each condition. Both representative pictures stem from the same membrane and exposure time. All western blots were normalized to total protein per lane. Original, unaltered images of all membranes and the gels that they were normalized to can be found in the data supplement. n = 12, ** indicates a p-value of <0.01 and **** indicates a p-value of <0.0001.