Table 3.
OHCA category | > I | > II | > III |
---|---|---|---|
Cut-off 20 points | Cut-off 40 points | Cut-off 60 points | |
A: mortality at 2 years | |||
Total number of patients n | 231 | 93 | 8 |
2-year survivors n (%) | 48 (20.8) | 2 (2.1) | 0 (0) |
Death within 2 years n (%) | 183 (79.2) | 91 (97.9) | 8 (100) |
Sensitivity | 75.9 (70.0, 81.2) | 37.8 (31.6, 44.2) | 3.3 (1.4, 6.4) |
Specificity | 72.4 (65.1, 78.9) | 98.9 (95.9, 99.9) | 100.0 (97.9, 100.0) |
PPV | 79.2 (73.4, 84.3) | 97.8 (92.4, 99.7) | 100.0 (63.1, 100.0) |
NPV | 68.5 (61.2, 75.1) | 53.4 (47.8, 59.0) | 42.8 (37.9, 47.7) |
LLR + | 2.75 (2.14, 3.54) | 32.85 (8.20, 131.55) | n. a |
LLR− | 0.33 (0.26, 0.42) | 0.63 (0.57, 0.70) | 0.97 (0.94, 0.99) |
B: mortality at 6 years | |||
Total number of patients n | 202 | 93 | 8 |
6-year survivors n (%) | 19 (9.4) | 2 (2.1) | 0 (0) |
Death within 6 years n (%) | 183 (90.6) | 91 (97.9) | 8 (100) |
Sensitivity | 75.9 (70.0, 81.2) | 37.8 (31.6, 44.2) | 3.3 (1.4, 6.4) |
Specificity | 62.7 (48.1, 75.9) | 96.1 (86.5, 99.5) | 100.0 (93.0, 100.0) |
PPV | 90.6 (85.7, 94.2) | 97.8 (92.4, 99.7) | 100.0 (63.1, 100.0) |
NPV | 35.6 (25.7, 46.3) | 24.6 (18.8, 31.2) | 18.0 (13.7, 22.9) |
LLR + | 2.04 (1.42, 2.93) | 9.63 (2.45, 37.82) | n. a |
LLR− | 0.38 (0.28, 0.52) | 0.65 (0.58, 0.73) | 0.97 (0.94, 0.99) |
C: neurological outcome at 2 years | |||
Total number of patients n | 212 | 93 | 8 |
Good neurological outcome n (%) | 27 (12.7) | 2 (2.1) | 0 (0) |
Poor neurological outcome n (%) | 185 (87.3) | 91 (97.9) | 8 (100) |
Sensitivity | 75.8 (69.9, 81.1) | 37.3 (31.2, 43.7) | 3.3 (1.4, 6.4) |
Specificity | 69.7 (59.0, 79.0) | 97.8 (92.1, 99.7) | 100.0 (95.9, 100.0) |
PPV | 87.3 (82.0, 91.4) | 97.8 (92.4, 99.7) | 100.0 (63.1, 100.0) |
NPV | 51.2 (42.0, 60.4) | 36.3 (30.2, 42.7) | 27.4 (22.6, 32.6) |
LLR + | 2.50 (1.81, 3.45) | 16.60 (4.18, 65.96) | n. a |
LLR− | 0.35 (0.27, 0.45) | 0.64 (0.58, 0.71) | 0.97 (0.95, 0.99) |
Data presented as mean (95% CI) unless otherwise specified
LLR + positive likelihood ratio, LLR− negative likelihood ratio, NPV negative predictive value, OHCA Out-of-Hospital Cardiac Arrest Score, PPV positive predictive value